Wound Closure

Plus Antibacterial Suture Portfolio

Plus Antibacterial Sutures: Solutions to address the risks you face today

There are many factors that can contribute to surgical site infections

Antibacterial sutures can address one of them

The Coated VICRYL® Plus Antibacterial (polyglactin 910) Suture label has changed to reflect the growing body of evidence

After incubation at 37ºC for 24 hours, bacterial colonies (dark red) are visible in all areas of a petri dish except for the "zone of inhibition" around a Plus Antibacterial Suture137,138,146

Surgical site infections (SSIs) are caused by many factors – some are controllable, while others are uncontrollable. Suture selection provides an opportunity to address a known risk factor for infection – bacterial colonization of the suture.179,185

Percutaneous sutures create a conduit for bacteria to enter the wound. Additionally, like all foreign bodies, when implanted, sutures are rapidly coated with tissue protein, creating sites for bacterial colonization. This colonization can lead to biofilm formation, which can increase the difficulty of treating an infection even in the presence of antibiotics.185,190,191

Plus Antibacterial Solutions are the only commercially available sutures with antibacterial protection.

  • Proven in vitro to kill bacteria and inhibit bacterial colonization of the suture for 7 days or more137,138,146
  • Effective against pathogens commonly associated with surgical site infections, including:
    • Staphylococcus aureus
    • Staphylococcus epidermidis
    • Methicillin-resistant Staphylococcus aureus (MRSA)
    • Methicillin-resistant Staphylococcus epidermidis (MRSE)
    • Escherichia coli*
    • Klebsiella pneumoniae*

As seen in the images below, bacteria (dark red) will grow in all areas of a petri dish except for the “zone of inhibition” on and around a Plus Antibacterial Suture.137

"Before" – Prior to incubation
"After" – Zone of inhibition at 24 hrs
MONOCRYL before and after comparison

A range of Plus Sutures are available to meet the needs of skin and fascial tissue repair, including MONOCRYL® Plus Antibacterial (poliglecaprone 25) Sutures and PDS® Plus Antibacterial (polydioxanone) Sutures.

Site References

  • * Applicable to MONOCRYL Plus Suture and PDS Plus Suture only
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