DERMABONDš PRINEO System incorporates a fast-setting liquid topical skin adhesive capable of adhering to most body tissue and many other materials, such as surgical gloves and stainless steel. Inadvertent contact with any body tissue, and any surfaces or equipment that are not disposable or that cannot be readily cleaned with a solvent such as acetone, should be avoided. Polymerization of the DERMABONDšPRINEO System liquid adhesive component may be accelerated by water or fluids containing alcohol. DERMABONDšPRINEO System should not be applied to wet wounds. DERMABONDšPRINEO System should not be applied to the eye. If contact of the liquid adhesive with the eye occurs, flush the eye copiously with saline or water. If residual liquid adhesive remains, apply topical ophthalmic ointment to help loosen the bond and contact an ophthalmologist. When closing facial wounds near the eye with DERMABONDšPRINEO System, position the patient so that any run-off of the liquid adhesive is away from the eye. The eye should be closed and protected with gauze. Prophylactic placement of petroleum jelly around the eye, to act as a mechanical barrier or dam, can be effective in preventing inadvertent flow of liquid adhesive into the eye. DERMABONDšPRINEO System will not adhere to skin precoated with petroleum jelly. Therefore, avoid using petroleum jelly on any skin area where DERMABONDš PRINEO System is intended to adhere. Use of DERMABONDš PRINEO System liquid adhesive component near the eye has inadvertently caused some patients eyelids to be sealed shut. In some of these cases, general anesthesia and surgical removal has been required to open the eyelid. DERMABONDš PRINEO System should not be used below the skin because the polymerized material is not absorbed by tissue and can elicit a foreign body reaction. DERMABONDšPRINEO System should not be used in high skin-tension areas or across areas of increased skin tension, such as knuckles, elbows, or knees, unless the joint will be immobilized during the skin healing period or unless skin tension has been removed by application of another wound closure device (e.g., sutures or skin staples) prior to application of DERMABONDšPRINEO System For complete product details, please see Instructions for Use.