Users should be familiar with surgical procedures and techniques involving absorbable sutures before employing MONOCRYL Plus Antibacterial suture for wound closure, as risk of wound dehiscence may vary with the site of application and the suture material used. Physicians should consider the in vivo performance (under ACTIONS section) when selecting a suture for use in patients. The use of this suture may be inappropriate in elderly, malnourished, or debilitated patients, or in patients suffering from conditions that may delay wound healing. Do not resterilize. Discard opened packages and unused sutures. As with any foreign body, prolonged contact of any suture with salt solutions, such as those found in the urinary or biliary tracts, may result in calculus formation. As an absorbable suture, MONOCRYL Plus Antibacterial suture may act transiently as a foreign body. Acceptable surgical practice should be followed for the management of contaminated or infected wounds. A s this is an absorbable suture material, the use of supplemental nonabsorbable sutures should be considered by the surgeon in the closure of the sites which may undergo expansion, stretching or distention, or which may require additional support. For complete product details, please see Instructions for Use.