The safety and effectiveness of PDS Plus Antibacterial sutures have not been established in neural tissue, adult cardiovascular tissue, microsurgery, or for contact with cornea or sclera. Under certain circumstances, notably rthopedic procedures, immobilization by external support may be employed at the discretion of the surgeon. Do not resterilize. Discard open packages and unused sutures. Do not use after expiration date. For complete product details, please see Instructions for Use.